Daniel Sturridge, Josh McEachran and Patrick van Aanholt start in an otherwise experienced line-up.
Van Aanholt comes in for Ashley Cole who is not involved in the 18, while McEachran replaces Michael Essien who is on the bench.
Sturridge will play on the left of a front three with Nicolas Anelka in the centre and Salomon Kalou on the right. Didier Drogba is on the bench.
Ipswich make three changes in midfield and bring former Wigan striker Jason Scotland back into attack.
Chelsea are expected to line up in the following 4-3-3 formation:
1 Petr Cech
17 Jose Bosingwa
2 Branislav Ivanovic
26 John Terry (c)
38 Patrick van Aanholt
7 Ramires
46 Josh McEachran
8 Frank Lampard
21 Salomon Kalou
39 Nicolas Anelka
23 Daniel Sturridge
Subs: 40 Hilario, 19 Paulo Ferreira, 43 Jeffrey Bruma, 5 Michael Essien, 44 Gael Kakuta, 15 Florent Malouda, 11 Didier Drogba.
Så blev de tre jeg efterlyste som skulle bænkes, bænket. Kom så drenge!
Hellere et usundt legeme end en fordærvet sjæl